Actions
Export to: EndNote | Zotero | Mendeley
Collections
This file is not currently in any collections.
Data and Software for Degiacomi et al, Structure, 2017 Open Access
Research paper highlights: - Accounting for protein dynamics is key to measurement of cross-linking distances. - DynamXL is software that explicitly accommodates dynamics in cross-linking - DynamXL models side-chain rotamers and allows analysis of structural ensembles. - This method improves data interpretation and protein docking performance.
Descriptions
- Resource type
- Dataset
- Contributors
- Creator:
Degiacomi, Matteo T.
1
Contact person: Degiacomi, Matteo T. 1
Data collector: Degiacomi, Matteo T. 1
Data curator: Degiacomi, Matteo T. 1
Creator: Benesch, Justin L. P. 2
Contact person: Benesch, Justin L. P. 2
Creator: Schmidt, Carla 3
Creator: Baldwin, Andrew J. 2
1 Durham University, UK
2 University of Oxford, UK
3 Martin Luther University Halle-Wittenberg, Germany
- Funder
-
Schweizerische Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Biotechnology and Biological Sciences Research Council
Engineering and Physical Sciences Research Council
Royal Society
- Research methods
- Other description
-
Data and Software supporting Degiacomi et al study about a new method and associated software, DynamXL, that accommodates intrinsic protein dynamics in the modelling of cross-linking data. This approach substantially reduces error rates, leading to higher confidence in structure assessment and improved protein-protein docking.
- Keyword
- cross-linking
molecular modelling
protein docking
mass spectrometry
computational structural biology
- Subject
-
Molecular structure
Proteins--Crosslinking
Mass spectrometry
Computational biology
Computer software
- Location
- Language
- English
- Cited in
- Identifier
- ark:/32150/r27s75dc36z
doi:10.15128/r27s75dc36z
- Rights
- All rights reserved All rights reserved
- Publisher
-
Durham University
- Date Created
File Details
- Depositor
- M.T. Degiacomi
- Date Uploaded
- 12 October 2017, 15:10:54
- Date Modified
- 13 October 2017, 10:10:03
- Audit Status
- Audits have not yet been run on this file.
- Characterization
-
File format: x-gzip (GZIP Format, GZIP)
Mime type: application/x-gzip
File size: 846926318
Last modified: 2017:10:12 16:26:24+01:00
Filename: 2017_Structure_dynamxl.tar.gz
Original checksum: b7b88e0566172fe88991dc984abd4323
| User Activity | Date |
|---|---|
| User M.T. Degiacomi has updated Data and Software for Degiacomi et al, Structure, 2017 | over 6 years ago |
| User M.T. Degiacomi has updated Data and Software for Degiacomi et al, Structure, 2017 | over 6 years ago |
| User M.T. Degiacomi has updated Data and Software for Degiacomi et al, Structure, 2017 | over 6 years ago |
| User M.T. Degiacomi has deposited 2017_Structure_dynamxl.tar.gz | over 6 years ago |